Conspiracy theorists don't need to burden themselves with the facts.
I often see people claiming that lyme disease is a bioweapon created by the US government in the 50s and 60s. This seems to be popular among internet communist circles but also with the far right. Yet Borrelia burgdorferi DNA (in particular, regions of the ospA gene) has been detected via PCR in museum specimens collected as early as 1894 (Marshall III et al., 1994) and more recently from the 1940s (Persing et al., 1990). Furthermore the presentation of erythema migrans following a tick bite was first described by a Swede in the 1909. So what the fuck?
Diseases we had almost wiped out with vaccines keep coming back, we've had outbreaks of measles around the country lately.
And we're in deep shit if there is enough retards refusing corona vaccineS, from what I understand flu viruses are the most resilient and mutation-happy buggers around, no room for naysayers.
So there are some reasons to be a bit cautious when talking about this specific vaccine, as coronaviruses have this weird quirk called immune enhancement.
In some data analyzed in a feline corona virus model, scientist found that an infection (vaccine induced or otherwise) could trigger an immune response that is "improper" (for lack of a better word), and the created antibodies actually help the virus enter host cells. While this would lead to one nasty infection, the worst part about this is that your body will remember how to make these shitty antibodies, so if you get exposed to the virus again, your symptoms will we worse.
Now, a lot of viruses have this quirk, and vaccines work fine, as there are plenty of clinical trials. The main thing that is concerning about this new vaccine is all of the corner cutting.
While I believe that the resulting vaccine will be mostly safe, I doubt that it will be super effective.